{
  "id": "oai:papers.qnfo.org:hydrodynamic-gating-of-nuclear-spin-coherence",
  "slug": "hydrodynamic-gating-of-nuclear-spin-coherence",
  "title": "Hydrodynamic Gating of Nuclear Spin Coherence v2",
  "authors": [
    "Rowan Brad Quni-Gudzinas"
  ],
  "abstract": "Standard neurobiological models assume the mammalian brain is too warm and wet to sustain macroscopic quantum states, creating a “thermal wall” that seemingly precludes quantum cognition. However, the “viscosity paradox” of the cytoplasm reveals that while the cellular interior is structurally rigid, it retains transient, low-viscosity domains at the nanoscale. Here, a viscoelastic gating mechanism is introduced wherein the coherence of nuclear spin qubits is regulated by the sol-gel transitions of the actin cytoskeleton. Numerical analysis demonstrates that motional narrowing in the liquid “sol” phase extends the coherence time of phosphorus-31 spins in Posner molecules to over 80 seconds, while the collapse into the “gel” phase triggers a rapid readout via dipolar locking. To address thermodynamic constraints on isotopic purity, a mitochondrial assembly pathway is proposed that filters decoherent magnesium isotopes. This hydrodynamic framework resolves the thermal constraint, identifying the Posner molecule as a viable biological qubit protected by the rheology of the cell itself.",
  "abstract_markdown": "Standard neurobiological models assume the mammalian brain is too warm and wet to sustain macroscopic quantum states, creating a “thermal wall” that seemingly precludes quantum cognition. However, the “viscosity paradox” of the cytoplasm reveals that while the cellular interior is structurally rigid, it retains transient, low-viscosity domains at the nanoscale. Here, a viscoelastic gating mechanism is introduced wherein the coherence of nuclear spin qubits is regulated by the sol-gel transitions of the actin cytoskeleton. Numerical analysis demonstrates that motional narrowing in the liquid “sol” phase extends the coherence time of phosphorus-31 spins in Posner molecules to over 80 seconds, while the collapse into the “gel” phase triggers a rapid readout via dipolar locking. To address thermodynamic constraints on isotopic purity, a mitochondrial assembly pathway is proposed that filters decoherent magnesium isotopes. This hydrodynamic framework resolves the thermal constraint, identifying the Posner molecule as a viable biological qubit protected by the rheology of the cell itself.",
  "date": "2025-12-01",
  "first_published": "2025-12-01",
  "last_revised": "2025-12-01T00:00:00Z",
  "modified": "2025-12-01T00:00:00Z",
  "version": "1.0.0",
  "version_count": 1,
  "language": "en",
  "keywords": [],
  "quality_tags": [
    "High-quality scholarly research",
    "open-access scholarly work",
    "versioned research publication"
  ],
  "quality_label": "High-quality scholarly research",
  "quality_basis": "QNFO publisher classification for open-access, versioned research with a public revision history and reader correction channel; this is not a claim of independent peer review.",
  "quality_evidence_url": "https://qnfo.org/about",
  "peer_review_status": "Not independently peer-reviewed",
  "resource_type": "ScholarlyArticle",
  "doi": null,
  "doi_url": null,
  "url": "https://papers.qnfo.org/papers/hydrodynamic-gating-of-nuclear-spin-coherence",
  "license_url": "https://legal.qnfo.org/",
  "license_spdx": null,
  "sha256": "5faac2d2a72c91a5ada0e4dbba6c431938ce105571e0ff126f511a6537fb1515",
  "version_url": "https://papers.qnfo.org/papers/hydrodynamic-gating-of-nuclear-spin-coherence/v/1.0.0",
  "datacite": {
    "schemaVersion": "http://datacite.org/schema/kernel-4",
    "identifiers": [
      {
        "identifier": "https://papers.qnfo.org/papers/hydrodynamic-gating-of-nuclear-spin-coherence",
        "identifierType": "URL"
      }
    ],
    "creators": [
      {
        "name": "Rowan Brad Quni-Gudzinas",
        "nameType": "Personal",
        "nameIdentifiers": [
          {
            "nameIdentifier": "https://orcid.org/0009-0002-4317-5604",
            "nameIdentifierScheme": "ORCID",
            "schemeUri": "https://orcid.org"
          }
        ]
      }
    ],
    "titles": [
      {
        "title": "Hydrodynamic Gating of Nuclear Spin Coherence v2"
      }
    ],
    "publisher": "QNFO",
    "publicationYear": "2025",
    "resourceType": {
      "resourceTypeGeneral": "Text",
      "resourceType": "ScholarlyArticle"
    },
    "subjects": [
      {
        "subject": "High-quality scholarly research",
        "subjectScheme": "QNFO publisher classification",
        "schemeUri": "https://qnfo.org/about"
      },
      {
        "subject": "open-access scholarly work",
        "subjectScheme": "QNFO publisher classification",
        "schemeUri": "https://qnfo.org/about"
      },
      {
        "subject": "versioned research publication",
        "subjectScheme": "QNFO publisher classification",
        "schemeUri": "https://qnfo.org/about"
      }
    ],
    "dates": [
      {
        "date": "2025-12-01",
        "dateType": "Issued"
      },
      {
        "date": "2025-12-01",
        "dateType": "Updated"
      }
    ],
    "language": "en",
    "version": "1.0.0",
    "rightsList": [
      {
        "rightsUri": "https://legal.qnfo.org/"
      }
    ],
    "descriptions": [
      {
        "description": "Standard neurobiological models assume the mammalian brain is too warm and wet to sustain macroscopic quantum states, creating a “thermal wall” that seemingly precludes quantum cognition. However, the “viscosity paradox” of the cytoplasm reveals that while the cellular interior is structurally rigid, it retains transient, low-viscosity domains at the nanoscale. Here, a viscoelastic gating mechanism is introduced wherein the coherence of nuclear spin qubits is regulated by the sol-gel transitions of the actin cytoskeleton. Numerical analysis demonstrates that motional narrowing in the liquid “sol” phase extends the coherence time of phosphorus-31 spins in Posner molecules to over 80 seconds, while the collapse into the “gel” phase triggers a rapid readout via dipolar locking. To address thermodynamic constraints on isotopic purity, a mitochondrial assembly pathway is proposed that filters decoherent magnesium isotopes. This hydrodynamic framework resolves the thermal constraint, identifying the Posner molecule as a viable biological qubit protected by the rheology of the cell itself.",
        "descriptionType": "Abstract"
      },
      {
        "description": "Publisher quality classification: High-quality scholarly research. QNFO publisher classification for open-access, versioned research with a public revision history and reader correction channel; this is not a claim of independent peer review.",
        "descriptionType": "Other"
      },
      {
        "description": "Peer review status: Not independently peer-reviewed",
        "descriptionType": "Other"
      }
    ],
    "formats": [
      "text/html"
    ]
  }
}